Four different mutants of the protein TEM-1 in four entries.

Cyclic amide hydrolase (beta-lactamase) (E.C. 3.5.2.6)

The first and second authors contributed equally to this work.
Backbone dynamics of TEM-1 determined by NMR: evidence for a highly ordered protein.

The sequence numbering starts at H26 and is sequential to W288.

Tem-1 Beta-Lactamase From Escherichia Coli Inhibited With An Acylation Transition State Analog

Crystal Structure Of The Imipenem Inhibited Tem-1 Beta-Lactamase From Escherichia Coli

Crystal Structure Of Escherichia Coli Tem1 Beta-Lactamase At 1.8 Angstroms Resolution

N276d Mutant Of Escherichia Coli Tem-1 Beta-Lactamase

X-Ray Crystal Structure Of Tem-1 Beta Lactamase In Complex With A Designed Boronic Acid Inhibitor (1r)-1-Acetamido-2-(3-Carboxy

X-Ray Crystal Structure Of Tem-1 Beta Lactamase In Complex With A Designed Boronic Acid Inhibitor (1r)-2- Phenylacetamido-2-(3-

X-Ray Crystal Structure Of Tem-1 Beta Lactamase In Complex With A Designed Boronic Acid Inhibitor (1r)-1-Acetamido-2- (3-Carbox

Molecular Structure Of The Acyl-Enzyme Intermediate In Tem- 1 Beta-Lactamase

Crystal Structure Of Tem52 Beta-Lactamase

Crystal Structure Of Beta-Lactamase Inhibitor Protein-Ii In Complex With Tem-1 Beta-Lactamase

Crystal Structure Of Tem-1 Beta-lactamase / Beta-lactamase Inhibitor Protein Complex

Crystal Structure Of N132a Mutant Of Tem-1 Beta-Lactamase In Complex With A N-Formimidoyl-Thienamycine

Structure Of M182t Mutant Of Tem-1 Beta-Lactamase

Crystal Structure Of G238a Mutant Of Tem-1 Beta-Lactamase In Complex With A Boronic Acid Inhibitor (Sefb4)

Crystal Structure Of Tem-64 Beta-Lactamase In Complex With A Boronic Acid Inhibitor (105)

Crystal Structure Of Tem-30 Beta-lactamase At 2.0 Angstrom

Crystal Structure Of Tem-32 Beta-Lactamase At 1.6 Angstrom

Crystal Structure Of Tem-34 Beta-lactamase At 1.5 Angstrom

Ultra High Resolution Crystal Structure Of Tem-1

Crystal Structure Of The Complex Between M182t Mutant Of Tem-1 And A Boronic Acid Inhibitor (Sm2)

Crystal Structure Of The Complex Between M182t Mutant Of Tem-1 And A Boronic Acid Inhibitor (Nbf)

Crystal Structure Of The Complex Between M182t Mutant Of Tem-1 And A Boronic Acid Inhibitor (Cxb)

Crystal Structure Of The Complex Between M182t Mutant Of Tem-1 And A Boronic Acid Inhibitor (105)

Tem-1 Beta-lactamase In Complex With A Novel, Core- Disrupting, Allosteric Inhibitor

6 Alpha Hydroxymethyl Penicilloic Acid Acylated On The Tem- 1 Beta-Lactamase From Escherichia Coli

The Modular Architecture Of Protein-Protein Binding Site

Crystal Structure Of Tem-76 Beta-Lactamase At 1.4 Angstrom Resolution

Structural Insight Into The Kinetics And Cp Of Interactions Between Tem-1-Lactamase And Blip

Structural Insight Into The Kinetics And Delta-Cp Of Interactions Between Tem-1 Beta-Lactamase And Blip

Tem-1 Class-A Beta-Lactamase L201p Mutant Apo Structure

Crystal Structure Of Beta-Lactamse Inhibitory Protein-I (Blip-I) In Complex With Tem-1 Beta-Lactamase

Structural And Biochemical Evidence That A Tem-1 {beta}- Lactamase Asn170gly Active Site Mutant Acts Via Substrate- Assisted Ca

The Crystal Structure Of The Extended Spectrum Beta-Lactamase Tem-72 Reveals Inhibition By Citrate

Crystal Structure Of Beta Lactamase In Pet-15b

Crystal Structure Of Stabilized Tem-1 Beta-lactamase Variant V.13

Crystal Structure Of M68l/m69t Double Mutant Tem-1

ampicillin resistance protein [Shuttle vector pHY320PLK]

Ap resistance protein [synthetic construct]

TEM-26B beta-lactamase [Klebsiella oxytoca]

ampicillinase, partial [Enterobacteria phage f1]

beta-lactamase [unidentified cloning vector]

extended spectrum beta-lactamase CAZ-2 - Klebsiella pneumoniae

extended spectrum beta-lactamase CAZ-7 - Klebsiella pneumoniae

beta-lactamase (EC 3.5.2.6) - fission yeast (Schizosaccharomyces pombe)

beta-lactamase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]

TEM beta-lactamase [Klebsiella pneumoniae]

beta lactamase [Erwinia amylovora ATCC BAA-2158]

RecName: Full=Beta-lactamase TEM; AltName: Full=IRT-4; AltName: Full=Penicillinase; AltName: Full=TEM-1; AltName: Full=TEM-16/C

RecName: Full=Beta-lactamase TEM; AltName: Full=Penicillinase; Flags: Precursor [Salmonella enterica subsp. enterica serovar Ty

RecName: Full=Beta-lactamase TEM-12; Flags: Precursor [Klebsiella oxytoca]

TPA: beta lactamase [Birmingham IncP-alpha plasmid]

NMR Investigation of Tyr105 Mutants in TEM-1 beta-lactamase Suggests Active-Site Dynamical Coupling

The enzymes were dissolved to a concentration of 0.8 mM in a 90 % H2O:10 % D2O solution containing 4 mM imidazole and 0.1 mM DSS (pH = 6.6). All NMR experiments were performed at 30?C on a Varian INOVA 600 spectrometer operating at a proton frequency of 599.739 MHz equipped with a z-axis gradient and a triple resonance cryoprobe.

Backbone 1H, 15N and 13C' assignments of mutants Y105W, Y105G, Y105N and Y105D of TEM-1 beta-lactamase
NMR Investigation of Tyr105 Mutants in TEM-1 beta-lactamase

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax

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