A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.

Residues 1-34 present the HIS and T7 Tag; Residues 35-131 the RRM domain.

Solution Structure Of Human Srsf2 (Sc35) Rrm

Solution Structure Of Human Srsf2 (Sc35) Rrm In Complex With 5'- Uccagu-3'

Solution Structure Of Human Srsf2 (Sc35) Rrm In Complex With 5'- Uggagu-3'

splicing factor, arginine/serine-rich 2 [Xenopus (Silurana) tropicalis]

RNA-binding protein PR264 [Gallus gallus]

serine/arginine-rich splicing factor 2 [Gallus gallus]

serine/arginine-rich splicing factor 2 [Rattus norvegicus]

serine/arginine-rich splicing factor 2 [Pan troglodytes]

serine/arginine-rich splicing factor 2 [Bos taurus]

serine/arginine-rich splicing factor 2 [Sus scrofa]

RecName: Full=Serine/arginine-rich splicing factor 2; AltName: Full=Protein PR264; AltName: Full=Splicing component, 35 kDa; Al

RecName: Full=Serine/arginine-rich splicing factor 2; AltName: Full=Splicing component, 35 kDa; AltName: Full=Splicing factor S

TPA: splicing factor, arginine/serine-rich 2 [Bos taurus]

50mM L-Arg; 50mM L-Glu; 20mM NaH2PO4; ph 5.5

Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Kollman