Amide chemical shifts of free and hyaluronan-bound Link_TSG6 at a range of pH values

Link_TSG6 without hyaluronan octasaccharides
Link TSG6 without hyaluronan octasaccharides

Determining the molecular basis for the pH-dependent interaction between the link module of human TSG-6 and hyaluronan.

Refined Solution Structure Of The Human Tsg-6 Link Module

Solution Structure Of The Human Tsg-6 Link Module In The Presence Of A Hyaluronan Octasaccharide

Crystal Structure Of The Human Tsg-6 Link Module

tumor necrosis factor, alpha-induced protein 6 [synthetic construct]

tumor necrosis factor-stimulated protein TSG-6 precursor [Bos taurus]

secreted hyaluronate binding protein [Oryctolagus cuniculus]

TNF-stimulated gene 6 protein [Mus musculus]

Tumor necrosis factor, alpha-induced protein 6 [Homo sapiens]

tumor necrosis factor-inducible gene 6 protein precursor [Bos taurus]

tumor necrosis factor alpha-induced protein 6 precursor [Equus caballus]

tumor necrosis factor-inducible gene 6 protein precursor [Oryctolagus cuniculus]

tumor necrosis factor-inducible gene 6 protein precursor [Macaca mulatta]

tumor necrosis factor-inducible gene 6 protein precursor [Homo sapiens]

RecName: Full=Tumor necrosis factor-inducible gene 6 protein; AltName: Full=TNF-stimulated gene 6 protein; Short=TSG-6; AltName

RecName: Full=Tumor necrosis factor-inducible gene 6 protein; AltName: Full=Hyaluronate-binding protein PS4; AltName: Full=TNF-

RecName: Full=Tumor necrosis factor-inducible gene 6 protein; AltName: Full=Hyaluronate-binding protein; AltName: Full=TNF-stim

TPA: tumor necrosis factor, alpha-induced protein 6 [Bos taurus]

Link_TSG6 and hyaluronan octasaccharide complex

switch the shifts of HE and NE of ARG residues

1mM 15N-labelled Link_TSG6 with and without 1mM HA octasaccharide present

samples made up in 10% D2O, 0.02 % (w/v) sodium azide

chemical shifts of amide H and N-H nuclei in Link_TSG6 at a range of pH values

chemical shifts of amide H and N-H nuclei in Link_TSG6 in compelx with HA8 at a range of pH values