Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with imatinib

ABL1 regulatory core SH3-SH2-Kinase domain (83-534) in complex with imatinib

imatinib inhibits tyrosine kinase activity of ABL

Abl kinase domain in complex with PD173955

Abl kinase domain in complex with imatinib

The molecular basis of Abelson kinase regulation by its αI-helix.

Abelson tyrosine kinase, cancer, chronic myelogenous leukemia, allosteric activation, aI-helix, asciminib, NMR

ABL SH3-SH2-Kinase Domain (residues 83-534)

co-expression with phosphatase PTP1 plus a separate plasmid lamda phosphatase LPP

experiment No. 238 and 239 need to be added

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with asciminib

Abl 1b isoform wild type SH3-SH2-KD (aa 83-519) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-519) in complex with imatinib

Abl 1b isoform wild type SH3-SH2-KD (aa 83-517) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-517) in complex with imatinib

Abl 1b isoform wild type SH3-SH2-KD (aa 83-515) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-515) in complex with imatinib

Abl 1b isoform E528K SH3-SH2-KD (aa 83-534) apo

Abl 1b isoform E528K SH3-SH2-KD (aa 83-534) in complex with imatinib

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with GNF-5

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with PD166326