Backbone Assignment of Human Polymerase Theta MOTIF 2 phosphorylated by PLK1

Human Polymerase Theta MOTIF 2 phosphorylated by PLK1

(2S)-2-amino-3-phosphonooxy-propanoic acid

(2S,3R)-2-amino-3-phosphonooxy-butanoic acid

Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.

polymerase; mitosis; DNA repair; double-strand break; phosphorylation; PLK1

In sequence : X corresponds to phosphorylated Serine, Z corresponds to phosphorylated Threonine.

MOTIF 2 corresponds to residues : 1540-1660 of human polymerase theta