1H, 15N, 13C, backbone resonance assignment of the human apo Alkbh5, pH 6.0

Selectively catalyzes the oxidative demethylation of the internal mRNA modification N6-methyladenosine

N 6-methyladenosine binding induces a metal-centered rearrangement that activates the human RNA demethylase Alkbh5.

Incorporated a HIS-Tag, N-terminal domain from the enzyme, EIN, and a TEV recognition cleavage site.