Solution structure of RBM39 RRM1 bound to U1 snRNA stem loop 3

Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.

10 mM sodium phosphate, 3 mM DTT, 1.2 mM [U-13C; U-15N] RBM39 RRM1, 1.5 mM U1 snRNA SL3, 90% H2O/10% D2O

10 mM sodium phosphate, 3 mM DTT, 1.2 mM [U-13C; U-15N] RBM39 RRM1, 1.5 mM U1 snRNA SL3, 100% D2O

Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Kollman