Solution Structure of the Mediator Gall11 KIX Domain of C. Glabrata

Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.

Solution Structure of Mediator of RNA polymerase II transcription subunit 15 (Gal11) KIX Domain

700 uM [U-99% 13C; U-99% 15N] Gal11p, 10 mM sodium phosphate, 2 mM potassium phosphate,
137 mM sodium chloride, 2.7 mM potassium chloride, 1 mM EDTA, 90% H2O/10% D2O.

The CCPN NMR assignment and data analysis application

The PDBe & CCPN Entry Completion Interface

Spectrum analysis, peak integration, distance restraint calibration

Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Kollman

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax

Department of Biochemistry, Cambridge CB2 1GA, UK