The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.

Residues 1-41 represent a non-native linker with an affinity tag

HUMAN HUR PROTEIN RRM3 AND DOMAIN MUTANTS S318D AND W261E

CIC bioGUNE: Center for Cooperative Research in Biosciences