Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans:Nosiheptide in Complex with TipAS

(2S,4S)-2-amino-4-hydroxy-pentanedioic acid

4-(hydroxymethyl)-3-methyl-1H-indole-2-carboxylic acid

(2Z)-2-amino-3-sulfanylprop-2-enoic acid

(2S,4S)-2-amino-4-hydroxypentanedioic acid (non-preferred name)

(Z)-2-amino-3-sulfanyl-prop-2-enoic acid

Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans

TipAS is the short isoform of TipA. It is the C terminal domain from residue M110 to P253.

Antibiotic Binding Domain Of A Tipa-Class Multidrug Resistance Transcriptional Regulator

Structural Basis Of A Thiopeptide Antibiotic Multidrug Resistance System From Streptomyces Lividans:promothiocin A In Complex W

Structural Basis Of A Thiopeptide Antibiotic Multidrug Resistance System From Streptomyces Lividans:nosiheptide In Complex With

transcriptional regulator [Streptomyces coelicolor A3(2)]

thiostreptin-induced protein [Streptomyces lividans]

HTH-type transcriptional activator TipA [Streptomyces lividans TK24]

transcriptional regulator [Streptomyces sp. CCM_MD2014]

thiostrepton inducible protein [Streptomyces lividans TK24]

MULTISPECIES: HTH-type transcriptional activator TipA [Streptomyces]

MULTISPECIES: transcriptional regulator [Streptomyces]

transcriptional regulator [Streptomyces aureofaciens]

RecName: Full=HTH-type transcriptional activator TipA

chemical shifts of TipAS in complex with the antibiotic promothiocin A

TipAS in complex with the antibiotic promothiocin A

15 N labeled TipAS in complex with nosiheptide

13C-15N TipAS in complex with nosiheptide

13C-15N TipAS, nosiheptide
in Deuterium

13C-15N TipAS, nosiheptide,
in Pf1 phage

Schwieters, Kuszewski, Tjandra and Clore

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax