The backbone 1H, 13C, 15N resonance assignment of FGFR1 kinase domain in its free form

NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 1.

Mass given is for non-isotopically labelled FGFR1 kinase

Sequence used here for human FGFR1 kinase domain (residues 455-765), contains a
mutated catalytic Asp (D623A) plus two additional mutations designed to improve
stability (C488A and C584S)

Members of the fibroblast growth factor receptor family (FGFR1 to 4) are key mediators of both developmental and disease-associated angiogenesis.

Crystal Structure Of The Tyrosine Kinase Domain Of Fibroblast Growth Factor Receptor 1 In Complex With Su4984 Inhibitor

Crystal Structure Of The Tyrosine Kinase Domain Of Fibroblast Growth Factor Receptor 1 In Complex With Su5402 Inhibitor

Crystal Structure Of The Tyrosine Kinase Domain Of Fibroblast Growth Factor Receptor 1

Crystal Structure Of The Tyrosine Kinase Domain Of Fgf Receptor 1 In Complex With Inhibitor Pd173074

Fgfr Tyrosine Kinase Domain In Complex With 3-(3- Methoxybenzyl)-7-Azaindole

Crystal Structure Of The Catalytic Domain Of Fgfr1 Kinase In Complex With Arq 069

Human Fgfr1 Kinase In Complex With Ch5183284

Crystal Structure Of Human Fibroblast Growth Factor Receptor 1 Kinase Domain In Complex With Compound 1

Crystal Structure Of Human Fibroblast Growth Factor Receptor 1 Kinase Domain In Complex With Compound 6

Crystal Structure Of Human Fibroblast Growth Factor Receptor 1 Kinase Domain In Complex With Compound 8

Crystal Structure Of Human Fibroblast Growth Factor Receptor 1 Kinase Domain In Complex With Pyrazolaminopyrimidine 1

Crystal Structure Of Human Fibroblast Growth Factor Receptor 1 Kinase Domain In Complex With Pyrazolaminopyrimidine 2

Crystal Structure Of Human Fibroblast Growth Factor Receptor 1 Kinase Domain In Complex With Pyrazolaminopyrimidine 3

Fibroblast Growth Factor Receptor 1 Kinase In Complex With Jk-p5

Fibroblast Growth Factor Receptor 1 Kinase In Complex With Jk-p3

Fgfr1 In Complex With Ponatinib (co-crystallisation).

Structure Of Fgfr1 In Complex With Azd4547 (n-{3-[2-(3,5- Dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5- Dimethylpiper

Crystal Structure Of Fgfr1 Kinase Domain In Complex With 7n

fibroblast growth factor receptor 1 isoform 1 precursor variant [Homo sapiens]

fibroblast growth factor receptor 1 isoform 2 precursor variant [Homo sapiens]

precursor polypeptide (AA -21 to 799) [Mus musculus]

Fibroblast Growth Factor Receptor, 2-Ig Domain+2 AA insert [Homo sapiens]

Fibroblast Growth Factor Receptor, 3 Ig-Domain Form [Homo sapiens]

fibroblast growth factor receptor (FGFr) transmembrane form [Homo sapiens]

fibroblast growth factor receptor [Homo sapiens]

heparin-binding growth factor receptor [Homo sapiens]

fibroblast growth factor receptor:ISOTYPE=1 beta

fibroblast growth factor receptor 1 isoform 2 precursor [Mus musculus]

fibroblast growth factor receptor 1 isoform 3 precursor [Mus musculus]

fibroblast growth factor receptor 1 precursor [Bos taurus]

fibroblast growth factor receptor 1 precursor [Pongo abelii]

fibroblast growth factor receptor 1 isoform 10 precursor [Homo sapiens]

RecName: Full=Fibroblast growth factor receptor 1; Short=FGFR-1; AltName: Full=Basic fibroblast growth factor receptor 1; Short

RecName: Full=Fibroblast growth factor receptor 1; Short=FGFR-1; Short=bFGF-R-1; AltName: Full=Basic fibroblast growth factor r

TPA: fibroblast growth factor receptor 1 [Bos taurus]

Triple Gradient probe, equipped with Cryoprobe

All the samples were run under the same conditions

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax