Solution structure of the complex of the PTB domain of SNT-2 and 19-residue
peptide (aa 1571-1589) of hALK

Fibroblast growth factor receptor substrate 3, ALK tyrosine kinase receptor

Chemical shift reference of 1H was based on the proton of water (4.784ppm at
298K) and then those of 15N and 13C were calculated based on their gyromagnetic
ratios.

Solution Structure Of The Complex Of The Ptb Domain Of Snt-2 And 19- Residue Peptide (aa 1571-1589) Of Halk

Solution Structure Of The Chimera Of The Ptb Domain Of Snt-2 And 19- Residue Peptide (aa 1571-1589) Of Halk

fibroblast growth factor receptor substrate 3 [synthetic construct]

FGFR signalling adaptor SNT-2 [Homo sapiens]

Fibroblast growth factor receptor substrate 3 [Homo sapiens]

fibroblast growth factor receptor substrate 3 [Bos taurus]

fibroblast growth factor receptor substrate 3 [Papio anubis]

fibroblast growth factor receptor substrate 3 [Macaca mulatta]

PREDICTED: fibroblast growth factor receptor substrate 3 isoform X1 [Equus caballus]

RecName: Full=Fibroblast growth factor receptor substrate 3; Short=FGFR substrate 3; AltName: Full=FGFR-signaling adaptor SNT2;

TPA: fibroblast growth factor receptor substrate 3 [Bos taurus]

anaplastic lymphoma kinase Ki-1 variant, partial [Homo sapiens]

fusion protein EML4-ALK variant 1 [Homo sapiens]

fusion protein EML4-ALK variant 2 [Homo sapiens]

ALK tyrosine kinase receptor precursor [synthetic construct]

nucleophosmin-anaplastic lymphoma kinase fusion protein [Homo sapiens]

anaplastic lymphoma kinase [Homo sapiens]

anaplastic lymphoma kinase receptor [Homo sapiens]

TRK-fused gene/anaplastic lymphoma kinase (Ki-1) fusion protein long form [Homo sapiens]

TRK-fused gene-anaplastic lymphoma kinase fusion protein [Homo sapiens]

ALK tyrosine kinase receptor precursor [Rattus norvegicus]

ALK tyrosine kinase receptor precursor [Homo sapiens]

ALK tyrosine kinase receptor precursor [Mus musculus]

PREDICTED: ALK tyrosine kinase receptor [Macaca mulatta]

PREDICTED: LOW QUALITY PROTEIN: ALK tyrosine kinase receptor [Equus caballus]

RecName: Full=ALK tyrosine kinase receptor; AltName: Full=Anaplastic lymphoma kinase; AltName: CD_antigen=CD246; Flags: Precurs

Chemical shift assignments of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK
Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK

0.37mM SNT-2 PTB domain [U-15N, 13C] in complex with hALK peptide (1:1),
20mM d-Tris-HCl, 100mM NaCl, 1mM d-DTT, 0.02% NaN3, 90% H2O, 10% D2O

RIKEN Structural Genomics/Proteomics Initiative (RSGI)
NPPSFA, National Project on Protein Structural and Functional Analyses
Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax